Below is a list of representative publications. For a complete list of publications please refer to Pubmed.

    1. Eleni A. Karavia, Panagiota C. Giannopoulou, Vassiliki Konstantinopoulou, Katerina Athanasopoulou, Theodosios D. Filippatos, Demosthenes Panagiotakos and Kyriakos E. Kypreos (2023) Medicines for Obesity: Appraisal of Clinical Studies withGrading of Recommendations, Assessment, Development, andEvaluation Tool. Nutrients, 15(3): 606 [PUBMED] [Cited by] [REPRINT]

    Eleftheria C. Sagiadinou, Eleni A. Karavia, Eva Xepapadaki, Evangelia Zvintzou, Aikaterini Hatziri, Dimitra-Sotiria Karampela, Panagiota C. Giannopoulou, Dionysios J. Papachristou, George Panayiotakopoulos, Kyriakos E. Kypreos (2022) Benefits of a fixed-dose combination of standardized P. mume extract with choline on adipose tissue mitochondrial metabolic activity and pancreatic β-islet secretory capacity in mice. Phytomedicine Plus 2 (2022) 100317 [REPRINT]

    Evangelia Zvintzou, Dimitra-Sotiria Karampela, Aggeliki Vakka, Eva Xepapadaki, Eleni A Karavia, Aikaterini Hatziri, Panagiota Giannopoulou and Kyriakos E. Kypreos (2021) High density lipoprotein in atherosclerosis and coronary heart disease: Where do we stand today? Vascul. Pharmacol. 141:106928. doi: 10.1016/j.vph.2021.106928 [PUBMED] [Cited by] [REPRINT]
    2. Eva Xepapadaki, Ioanna Nikdima, Eleftheria C. Sagiadinou, Evangelia Zvintzou and Kyriakos E. Kypreos (2021) High Density Lipoprotein and Type 2 Diabetes Mellitus: Is it the egg or the chicken? Diabetologia 64(9):1917-1926 DOI: 10.1007/s00125-021-05509-0 [PUBMED] [Cited by] [REPRINT]

    Vassilis Lazaris, Aikaterini Hatziri, Argyris Symeonidis and Kyriakos E. Kypreos (2021) The Lipoprotein Transport System in the Pathogenesis of Multiple Myeloma: Advances and Challenges. Front Oncol. 2021 Mar 26;11:638288. doi: 10.3389/fonc.2021.638288. [PUBMED] [Cited by] [REPRINT] 

    Eva Xepapadaki, Ioanna Nikdima, Evangelia Zvintzou, Eleni A. Karavia and Kyriakos E. Kypreos (2021) Tissue-specific functional interaction between apolipoproteins A1 and E in Cold-Induced Adipose Organ Mitochondrial Energy Metabolism. BBA Mol. Cell Biol. Lipids. 1866(3):158859. doi: 10.1016/j.bbalip.2020.158859  [PUBMED] [Cited by] [REPRINT]

    Christina Kalogeropoulou, Aikaterini Hatziri, Eva Xepapadaki, Odysseia Savvoulidou, Eleni A. Karavia, Evangelia Zvintzou, Caterina Constantinou and Kyriakos E. Kypreos (2019) Isoform and tissue dependent impact of apolipoprotein E on adipose tissue metabolic activation: the role of apolipoprotein A1. BBA Mol. Cell Biol. Lipids. 1865(2):158551. doi: 10.1016/j.bbalip.2019.158551. [PUBMED] [Cited by] [REPRINT]
    6. Eleni A. Karavia and Kyriakos E. Kypreos (2019) Pharmacological management of nonalcoholic fatty liver disease: limitations, challenges and new therapeutic opportunities. JAPT, 10(1):28–37 [PUBMED] [Cited by] [REPRINT]

    Evangelia Zvintzou, Eva Xepapadaki, Christina Kalogeropoulou, Serafoula Filou and Kyriakos E. Kypreos (2019) Pleiotropic Effects of Apolipoprotein A2 on High Density Lipoprotein Functionality, Adipose Tissue Metabolic Activity and Plasma Glucose Homeostasis. J. Biomed. Res., Jul 26;0(0):1-13. doi: 10.7555/JBR.33.20190048 [PUBMED] [Cited by] [REPRINT]

    Evangelia Zvintzou, Eva Xepapadaki, Christina Kalogeropoulou, Serafoula Filou and Kyriakos E. Kypreos (2019) Τhe antioxidant function of HDL in atherosclerosis Angiology, Jun 11:3319719854609. doi: 10.1177/0003319719854609. [PUBMED] [Cited by] [REPRINT]

    Eva Xepapadaki, Giuseppe Maulucci, Caterina Constantinou, Eleni A Karavia, Evangelia Zvintzou, Bareket Daniel, Shlomo Sasson and Kyriakos Kypreos (2019) Impact of apolipoprotein A1- or Lecithin:cholesterol acyltransferase-deficiency on white adipose tissue metabolic activity and glucose homeostasis in mice. Biochim Biophys Acta Mol Basis Dis., 1865(6):1351-1360 [PUBMED] [Cited by][REPRINT]
      Kyriakos E. Kypreos, Rafael Bitzur, Eleni A. Karavia, Eva Xepapadaki, George Panayiotakopoulos and Caterina Constantinou (2018) Pharmacological management of dyslipidemia in atherosclerosis: Limitations, challenges and new therapeutic opportunities. Angiology, 70(3): 197-209, doi: 10.1177/0003319718779533. [PUBMED] [Cited by] [REPRINT]

    Kyriakos E. Kypreos, Eleni A. Karavia, Caterina Constantinou, Aikaterini Hatziri, Christina Kalogeropoulou, Eva Xepapadaki, and Evangelia Zvintzou (2018) Apolipoprotein E in diet-induced obesity: a paradigm shift from conventional perception. J. Biomed. Res., 32(3):183-190. doi: 10.7555/JBR.32.20180007 [PUBMED] [Cited by] [REPRINT]

    Aikaterini Hatziri, Christina Kalogeropoulou, Eva Xepapadaki, Eleni Birli, Eleni A. Karavia, Eugenia Papakosta, Serafoula Filou, Caterina Constantinou and Kyriakos E. Kypreos (2017) Site-specific effects of apolipoprotein E expression on diet-induced obesity and white adipose tissue metabolic activation. Biochim Biophys Acta Mol Basis Dis., 1864(2):471-480. doi: 10.1016/j.bbadis.2017.11.007. [PUBMED] [Cited by] [REPRINT]

    13. Evangelia Zvintzou, Marie Lhomme, Stella Chasapi, Serafoula Filou, Vassilis Theodoropoulos, Eva Xapapadaki, Anatol Kontush, George Spyroulias, Constantinos C. Tellis, Alexandros D. Tselepis, Caterina Constantinou and Kyriakos E. Kypreos (2017) Pleiotropic Effects of Apolipoprotein C3 on HDL Functionality and Adipose Tissue Metabolic Activity. J. Lipid Res., 58(9):1869-1883, doi: 10.1194/jlr.M077925. [PUBMED] [Cited by] [REPRINT]

    Papachristou NI, Blair HC, Kypreos KE, Papachristou DJ. (2017) High-density lipoprotein (HDL) and bone mass. J. Endocrinol., 233(2):R95-R107 [PUBMED] [Cited by] [REPRINT]

    Filou S, Lhomme M, Karavia EA, Kalogeropoulou C, Theodoropoulos V, Zvintzou E, Sakellaropoulos GC, Petropoulou PI, Constantinou C, Kontush A, Kypreos KE. (2016) Distinct Roles of Apolipoproteins A1 and E in the Modulation of High-Density Lipoprotein Composition and Function. Biochemistry 55 (27), 3752-3762. [PUBMED] [Cited by] [REPRINT]

    Blair HC, Kalyvioti E, Papachristou NI, Tourkova IL, Syggelos SA, Deligianni D, Orkoula MG, Kontoyannis CG, Karavia EA, Kypreos KE, Papachristou DJ. (2016) Apolipoprotein A-1 regulates osteoblast and lipoblast precursor cells in mice. Lab Invest., 2016 Jul;96(7):763-72. [PUBMED] [Cited by] [REPRINT]

     Caterina Constantinou, Eleni A. Karavia, Eva Xepapadaki, Peristera-Ioanna Petropoulou, Eugenia Papakosta, Marilena Karavyraki, Evangelia Zvintzou, Vassilis Theodoropoulos, Serafoula Filou, Aikaterini Hatziri, Christina Kalogeropoulou, George Panayiotakopoulos and Kyriakos E. Kypreos (2015) Advances in High Density Lipoprotein Physiology: surprises, overturns and promises. Am J Physiol Endocrinol Metab., 2016 Jan 1;310(1):E1-E14. [PUBMED] [Cited by] [REPRINT]

    Eleni A. Karavia, Aikaterini Hatziri, Christina Kalogeropoulou, Nikolaos I Papachristou, Eva Xepapadaki, Caterina Constantinou, Anastasios Natsos, Peristera-Ioanna Petropoulou, Shlomo Sasson, Dionysios J Papachristou, and Kyriakos E. Kypreos (2015) Deficiency in apolipoprotein A-I ablates the pharmacological effects of metformin on plasma glucose homeostasis and hepatic lipid deposition. Eur. J. Pharmacol., 766:76-85 (10.1016/j.ejphar.2015.09.040) [PUBMED] [Cited by] [REPRINT]

    Eleni A. Karavia, Nikolaos I. Papachristou, George C. Sakellaropoulos, Eva Xepapadaki, Eleni Papamichail, Peristera-Ioanna Petropoulou, Eugenia P. Papakosta, Caterina Constantinou, Ioannis Habeos, Dionysios J. Papachristou, and Kyriakos E. Kypreos (2015) Scavenger receptor class B type I regulates plasma apolipoprotein E levels and dietary lipid deposition to the liver. Biochemistry 54(36):5605-16 (10.1021/acs.biochem.5b00700) [PUBMED] [Cited by] [REPRINT]

    Peristera-Ioanna Petropoulou, Jimmy F.P. Berbée, Vassilios Theodoropoulos, Aikaterini Hatziri, Panagiota Stamou, Eleni A. Karavia, Alexandros Spyridonidis, Iordanes Karagiannides and Kyriakos E. Kypreos (2015) Lack of LCAT reduces the LPS-neutralizing capacity of HDL and enhances LPS-induced inflammation in mice. Biochim Biophys Acta Mol Basis Dis., 1852:2106-2115. [PUBMED] [Cited by] [REPRINT]

    Catherina Constantinou, Diogenis Mpatsoulis, Anastasios Natsos, Peristera-Ioanna Petropoulou, Evangelia Zvintzou, Abdulmaged M. Traish, Peter J. Voshol, Iordanes Karagiannides, Kyriakos E. Kypreos (2014) The low density lipoprotein receptor modulates the effects of hypogonadism on diet-induced obesity and related metabolic perturbations. J Lipid Res., 55(7):1434-1447.[PUBMED] [Cited by] [FEATURED IN...] [REPRINT]

    Karavia EA, Zvintzou E, Petropoulou PI, Xepapadaki E, Constantinou C, Kypreos KE. (2014) HDL quality and functionality: what can proteins and genes predict? Expert Rev Cardiovasc Ther., 12(4):521-32. [PUBMED] [Cited by] [REPRINT]

    Evangelia Zvintzou, George Skroubis, Angelika Chroni, Peristera-Ioanna Petropoulou, Christina Gkolfinopoulou,George Sakellaropoulos, Donald Gantz, Ioanna Mihou, Fotios Kalfarentzos, Kyriakos E. Kypreos (2014) Effects of bariatric surgery on HDL structure and functionality: results from a prospective trial. J. Clin. Lipidol., 8(4):408-417 [PUBMED] [Cited by] [FEATURED IN...][REPRINT]

    Kyriakos E. Kypreos, Spyridon Gkizas, Loukianos S. Rallidis, Iordanis Karagiannides (2013) HDL particle functionality as a primary pharmacological target for HDL-based therapies. Biochemical Pharmacology. 85(11):1575-1578 [PUBMED] [Cited by] [REPRINT]

    Angeliki Lampropoulou, Vassilis I. Zannis, Kyriakos E. Kypreos (2012) Pharmacodynamic and pharmacokinetic analysis of apoE4 [L261A, W264A, F265A, L268A, V269A], a recombinant apolipoprotein E variant with improved biological properties. Biochemical Pharmacology, 84(11):1451-8. [PUBMED [Cited by] [REPRINT]

    Irene-Eva Triantaphyllidou, Eleni Karavia, Eleni Kalyvioti, Ioannis Lilis, Kyriakos E. Kypreos, and Dionysios J. Papachristou (2012) Perturbations in ithe HDL metabolic pathway predispose to the development of osteorthritis in mice follwoing long-term exposure to westen-type diet. Osteoarthritis Cartilage. 21(2):322-330 [PUBMED] [Cited by] [REPRINT]

    Eleni A. Karavia, Dionysios J. Papachristou, Kassiani Liopeta, Irene-Eva Triantafyllidou, Odyssefs Dimitrakopoulos, and Kyriakos E. Kypreos (2012) Apolipoprotein A-I modulates Processes Associated with Diet-Induced Nonalcoholic Fatty Liver Disease in Mice, Mol. Med., 18(1):901 [PUBMED] [Cited by] [REPRINT]

    Kyriakos E. Kypreos (2012) HDL Quality in Atherosclerosis: can ratios between apolipoproteins of HDL be used effectively to indicate risk of premature myocardial infarction? Clin. Lipidol., 7:127-29. (Invited Editorial). [PUBMED] [Cited by]

    Eleni Karavia, Dionysios J. Papachristou, Ioanna Kotsikogianni, Irene-Eva Triantafyllidou, and Kyriakos E. Kypreos (2012) Lecithin:cholesterol acyltransferase modulates the severity of diet-induced nonalcoholic fatty liver disease in mice. J. Nutr. Biochem., 24(3):567-577. [PUBMED] [Cited by] [REPRINT]

    Anthula E. Kavo, Loukianos Rallidis, George C. Sakellaropoulos, Stefan Lehr, Sonja Hartwig, Juergen Eckel, Polixeni Mpozatzi, Panagiota Tsikrika, and Kyriakos E. Kypreos (2012) Qualitative characteristics of HDL particles in young asymptomatic patients of an acute myocardial infarction. Atherosclerosis, 220:257-64. [PUBMED] [Cited by] [REPRINT]

    Eleni Karavia, Dionysios J. Papachristou, Ioanna Kotsikogianni and Kyriakos E. Kypreos (2011) Deficiency in Apolipoprotein E has a Protective effect on Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. FEBS J, 278:3119-29. [PUBMED] [Cited by] [REPRINT]

    Peristera A. Petropoulou, Donald L. Gantz, Yanan Wang, Patrick C.N. Rensen, and Kyriakos E. Kypreos (2011). The aminoterminal 1-185 domain of human apolipoprotein E suffices for the de novo biogenesis of apoE-containing HDL. Atherosclerosis, 219:116-23. [PUBMED] [Cited by] [REPRINT]

    Abdul Traish and Kyriakos E. Kypreos (2010) Testosterone and Cardiovascular Disease: An Old Idea with Modern Clinical Implications, Atherosclerosis, 214:244-8. [PUBMED] [Cited by] [REPRINT]

    Eirini M. Tsompanidi, Maria S. Brinkmeyer, Elisavet H. Fotiadou, Smaragda M. Giakoumi, and Kyriakos E. Kypreos (2010) HDL biogenesis and functions: Role of HDL quality and quantity in atherosclerosis. Atherosclerosis, 208: 3-9. [PUBMED] [Cited by] [REPRINT]


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